Rosalind Fox Solomon has entered closed circles across a diverse range of cultures. She has captured defining moments of the 20th century, from documenting the American South in her project Liberty Theater, to her groundbreaking series Portraits in the Time of AIDS. She has made bodies of work outside of the United States in Europe, Africa, Asia, and Latin America. In 2019, the ICP awarded Fox Solomon a Lifetime Achievement award in recognition of her prolific career. Among her other awards is a National Endowment for the Arts Fellowship, a Lucie Achievement in Portraiture, and a Guggenheim Fellowship.

Her talent lies in the capacity to interpret and photograph cultures in the places she travels. She incorporates the obsessions and anxieties that travel with her. She has also produced the installations Adios and Catacombs; handmade books; and two short video pieces, To Highlands and A Woman I Once Knew. Her MACK books include: THEM, Got to Go, Liberty Theater, and The Forgotten. In September 2024, MACK will release, A Woman I Once Knew.  

Fox Solomon has created challenging bodies of work, shown in nearly 30 solo exhibitions and more than 75 group exhibitions, and in the collections of museums around the world which include: MoMA, National Gallery of Art, Los Angeles County Museum, Metropolitan Museum of Art, SFMOMA, the Bibliothèque Nationale de France, Museo de Arte de Lima, National Gallery of Canada, the Rijksmuseum, and the Victoria and Albert Museum.

In 2021, MUUS acquired the Rosalind Fox Solomon Collection.